After Saturday's loss at Everton, Manchester United simply have to beat West Ham if they are to maintain hopes of keeping their title crown.
With the Carling Cup final taking place on Sunday, United's Premier League clash has been brought forward.
Chelsea face Manchester City while Arsenal are at Stoke so three points at Old Trafford will at least put some pressure on the champions' title rivals.
The price reflects the situation with The Red Devils a best-priced 2/9 to win.
Sir Alex Ferguson may shuffle his pack with Wembley in mind but he won't want to gamble too much after an impressive run of form came to an abrupt end at Goodison, particularly in the second half when they were very much second best.
West Ham are as big as 16/1 with Boylesports to cause a Hammer blow to United's hopes while Carlton Cole, clearly his team's biggest goal threat, is a tasty 14/1 to score first with Paddy Power.
But United will expect to win, especially if Rio Ferdinand and Nemanja Vidic are back in tandem for the first time since October, and 2-0 could be a correct-score opton at 11/2.