Arsenal and Manchester United face a gamble over the fitness of star turns Cesc Fabregas and Wayne Rooney in their midweek Champions League ties.
Arsene Wenger says he will risk midfielder and top scorer Fabregas if his hamstring injury is rated better than 50-50.
The Gunners trail Porto 2-1 and their chances of progressing will be seriously affected if the Spain international is missing.
Arsenal are a best-priced 8/13 which is short, even if Porto are considered poor travellers.
The Portuguese side, who proved they're no mugs in the first leg, are 11/2 in several places including Bet365.
United are in a better position as they hold a 3-2 advantage over Milan.
Rooney scored twice in the San Siro and is the man the Italians fear.
United were pretty poor without him at Wolves and very fortunate to escape with the three points.
Although Sir Alex Ferguson has made his point about his star striker playing for England despite carrying a minor knee injury, it seems likely the country's top scorer will start at Old Trafford.
Wes Brown is out though and there are fears he's broken his foot - which could rule him out of World Cup contention.
United are a best-priced 8/11 with Victor Chandler with Milan at 9/2.
Our guess is both Fabregas and Rooney will play because the stakes are so high. The Spaniard could start on the bench and, if that's the case, Porto will fancy their chances of squeezing through in a major shock.