Mr Pointment and Abbeybraney were this morning declared non-runners for tomorrow's John Smith's Grand National, paving the way clear for Cerium and Royal Rosa to run in the race.
North Yorkshire trainer Paul Murphy issued a veterinary certificate for Mr Pointment and is to rely upon stablemate Cerium, who finished fifth last year and will be ridden by Davy Russell.
Howard Johnson has also substituted Royal Rosa for Abbeybraney after the latter had not eaten up overnight. The 11-year-old will be partnered by Wilson Renwick.
First-reserve Silver Birch has also been withdrawn, and will run in this afternoon's John Smith's Topham Chase (3.45).
Knowhere, the fourth reserve on the initial National list, has been eliminated